Designer Oncolytic Adenovirus: Coming of Age

Increasing the Efficacy of Oncolytic Adenovirus Vectors

Oncolytic adenovirus (Ad) vectors present a new modality to treat cancer. These vectors attack tumors via replicating in and killing cancer cells. Upon completion of the vector replication cycle, the infected tumor cell lyses and releases progeny virions that are capable of infecting neighboring tumor cells. Repeated cycles of vector replication and cell lysis can destroy the tumor. Numerous Ad...

Coming of Age

Emotion Coming of Age

A s the articles in this special issue attest to, emotion is finally coming of age. Affect, as many of the authors suggest, serves a function—it aids survival, and affect regulation is a key human motive. People seek emotions because what emotion makes them feel—the conscious feelings of such things as pain and pleasure—aids survival by promoting approach and avoidance and other action tendenci...

Coming of Age

a guide to ageing well with HIV new version 2013 JUSTRI is a UK-based not-for-profit organisation, dedicated to providing resources and education for those with and working with HIV and viral hepatitis. JUSTRI Slide is a free, online, searchable, downloadable slide library with many presentations about HIV and ageing. Access them at www.justrislide.com " I thought that I would be grown up when ...

Coming of age.

In Australia, as in many Western countries, the population is ageing. In coming decades we can anticipate that the medical care of the elderly will claim an increasing proportion of medical and economic resources. It will also confront us with an expanding challenge in the ethical issues affecting the aged. One can easily define the ingredients in the Antipodean problem but the solutions are no...